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TREATMENT OF DM: ORAL HYPOglycaemics
The document outlines various oral hypoglycemic treatments for managing diabetes mellitus (DM), detailing different classes of medications such as biguanides, thiazolidinediones (glitazones)
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TREATMENT OF DM: ORAL HYPOglycaemics Alpha GluCOSidase Inhibitors BIGuANIDES Prandial Glucose Regulators (PGR) SulphoNYLureas S.Es Secondary failure rate = 5-10% per yr Hypoglycaemia WEIGHT GAIN by increasing inulin secretion Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal Effective, well-tolerated & widely used No lag period b4 response High initial response INCREASE insulin secretion Examples: ChlorPROpaMIDE TolBUTAmide GliPIzide GliCLAzide GliBENclaMIDE ThiaZOlidiNEdiones (GlitaZONES)
