Organophosphate Poisoning

Mild Acute Poisoning (Sheep dip flu)

Small or pinpoint pupils

Painful. blurred vison

Runny nose and eyes

Excess saliva

Headache

Nausea

Mild muscle weakness

Moderate OPP

Pinpoint pupils, conjunctival injection

Dizziness, disorientation

Coughing, wheezing, sneezing

Drooling, excess phlegm, bronchorrhoea, bronchospams

Difficulty breathing

Vomiting, diarrhoea, urination

Severe OPP

Pinpoint pupils

Confusion and agitation

Conculsions

Copious excess secretions

Cardiac arrhythmias

Collapse, respiratory depression or arrest

Coma

Death

Maintain Airway

Remove Clothing

Wash down

For Mild Symptoms

Consider Atropine 0.6-4mg IV

0.5% tropicamide eye drops

For Moderate and Severe

Establish IV access

Give Atropine ASAP

Adult Dose 0.6-4.0 mg IV

Pediatric 20 mcg/kg IV

Pralidoxime

Adult 30 mg/kg IV over 4 mins

Infuse 8-10mg/kg/hr

Diazepam

Adult 5-10mg IV

Pediatric 1-5mg IV

Repeat as required

Intubate and ventilate

Severe Respiratory Distress or Apnoea

Monitor ECG

Treat any arrhythmias

Pesticides

Herbicides

Nerve Gas

Less commonly seen

high mortality rate

dangerous for all persons

consider proper PPE