6 years plan
for
Ancient DNA
(Paleogenomics)
Lab @QU

Precision Medicine

Precision Medicine

QU-Health Precision Medicine RNG

Drug Development

Disease Diagnosis

Immunology

Objectives

Objectives

Track presence/absence of pathogenic and deleterious mutations in ancient and modern human

Look at the distribution, variation, and effects of viruses

becoming non-infectious after some time

e.g. HERVs

becoming infectious after time

e.g. HTLV-1 & Lymphoma

trigger for other diseases

e.g. HHV-6 & multiple sclerosis

Ancient migratory patterns contributing to increased predisposition or resistance to diseases

To establish an ancient DNA lab @ QU with guidance from HMS

Grant

Grant

PPM

ARG

Disease/Conditions

Disease/Conditions

Artherosclerosis

Obesity and dyslipidemia

Diabetes and insulin resistance

Team

Team

Dr Mashael (CHS)
(Geneticist)

Dr Mashael (CHS)
(Geneticist)

Dr Rozaimi (CHS)
(Computational Biologist)

Dr Rozaimi (CHS)
(Computational Biologist)

Dr Houssein (CHS)
(Population geneticist)

Dr Houssein (CHS)
(Population geneticist)

Dr Sherine (CAS)
(Archaeologist)

Dr Sherine (CAS)
(Archaeologist)

Dr Hanaa Mousa (CMED)
(Immunologist)

Dr Hanaa Mousa (CMED)
(Immunologist)

Dr David Reich
(Paleogeneticist)

Dr David Reich
(Paleogeneticist)

Dr Suad Al Fadhli

Dr Maryam Daneshpour

Partner

Partner

To provide ancient bone samples

To provide ancient samples

To provide ancient samples

To provide sequencing service

To provide sequencing service

To provide sequencing saervice

To provide sequencing saervice

To provide ancient DNA analysis and training

To provide ancient DNA analysis and training

To provide modern DNA

To provide modern DNA

Cancer

Grant

ARG

PPM

Case study

Team

Dr Hamda Al Thawadi (CMED)

Dr Semir (CMED)

Forensic

Ethics

Ethics

CILE (HBKU)

Dr Mohammed Ghaly

Conservation

Conservation

Dugong

QU BRC

Turtle

Shark

Camel

History

History

Subtopic